2015
Stereochemical Bias Introduced during RNA Synthesis Modulates the Activity of Phosphorothioate SiRNAs
H. Jahns, M. Roos, J. Imig, F. Baumann, Y. Wang, R. Gilmour and J. Hall
Nat Commun. 2015 (external pagePubMed)
“Full PS-siRNAs – where potency is determined by the activator!”Prof. Jonathan Hall
Polyamine-oligonucleotide Conjugates: a Promising Direction for Nucleic Acid Tools and Therapeutics
M. Menzi, H. L. Lightfoot and J. Hall*
Future Medicinal Chemistry 2015 (external pagePubMed)
MiR-CLIP Capture of a MiRNA Targetome Uncovers a lincRNA H19-miR-106a Interaction
J. Imiga, A. Brunschweigera, A, Brümmer, B. Guennewig, N. Mittal, S. Kishore, P. Tsikrika, A. P. Gerber, M. Zavolan, and J. Hall
Nat Chem Biol. 2015 (external pagePubMed)
Paper highlighted in Nature Chemical Biology News and Views 2015 11(2), 100 and in Chimia Concentrates 2015 69(5).
Short Loop-targeting Oligonucleotides Antagonize Lin28 and Enable Pre-let-7 Processing and Suppression of Cell Growth in let-7-Deficient Cancer Cells
M. Roos, M. A. E. Rebhan, M. Lucic, D. Pavlicek, U. Pradère, H. Towbin, G. Civenni, C. V. Catapano and J. Hall
Nucleic Acids Res. 2015 (external pagePubMed)
Properties of Short Double-stranded RNAs Carrying Randomized Base Pairs: Toward Better Controls for RNAi Experiments
J. A. Zagalak, M. Menzi, F. Schmich, H. Jahns, A. M. Dogar, F. Wullschleger, H. Towbin and J. Hall
RNA. 2015 (external pagePubMed)
“Just amazing how fast randomized passenger and guide RNAs find their complementary partners”Prof. Jonathan Hall