2016
A Small-Molecule Inhibitor of Lin28
M. Roos, U. Pradère, P. Ngondo, A. Behera, S. Allegrini, G. Civenni, J. A. Zagalak, J.-R. Marchand, M. Menzi, H. Towbin, J. Scheuermann, D. Neri, A.Caflisch, C. V. Catapano, C. Ciaudo and J. Hall
ACS Chem Biol. 2016 (external pagePubMed)
Paper highlighted in Molecules Editorial “Breakthroughs in Medicinal Chemistry” 2017 (external pagePubMed)
“From assay design through screening to validation in stem cells - the first direct small molecule LIN28 inhibitor”Prof. Jonathan Hall
“From assay design through screening to validation in stem cells - the first direct small molecule LIN28 inhibitor”Prof. Jonathan Hall
Site-specific Conjugation of Drug-like Fragments to an AntimiR Scaffold as a Strategy to Target MiRNAs Inside RISC
A. Brunschweigera, L. F. R. Geberta, M. Lucic, U. Pradère, H. Jahns, C. Berk, J. Hunziker and J. Hall
Chem Commun 2016 (external pagePubMed
“Essential reading for antimiR chemists – Stay away from position 6!”Prof. Jonathan Hall
Site-specific Labeling of microRNA Precursors: a Structure Activity Relationship Study
M. Menzi, U. Pradère, Y. Wang, M. Fischer, F. Baumann, M. Bigatti and J. Hall
ChemBioChem 2016 (external pagePubMed)
Site-Specific Difunctionalization of Structured RNAs Yields Probes for microRNA Maturation
U. Pradère and J. Hall
Bioconjug Chem. 2016 (external pagePubMed)