2017
Type III CRISPR-Cas systems produce cyclic oligoadenylate second messengers
O. Niewoehner, C. Garcia-Doval, J.T. Rostøl, C. Berk, F. Schwede, L. Bigler, J. Hall, L.A. Marraffini and M. Jinek
Nature 2017 (external pagePubMed)
Towards improved oligonucleotide therapeutics through faster target binding kinetics
M. Menzi, B Wild, U. Pradère, A. L. Malinowska, A. Brunschweiger, H. L. Lightfoot and J. Hall
Chemistry 2017 (external pagePubMed)
“Huge increases in kon from a Nature-inspired modification”Prof. Jonathan Hall
Chemical Synthesis of Long RNAs with Terminal 5'-Phosphate Groups
U. Pradère, F. Halloy and J. Hall
Chemistry 2017 (external pagePubMed)
“Finally! A decent synthetic reagent for terminal phosphorylation of RNAs on solid phase”Prof. Jonathan Hall
Synthesis and Cellular Activity of Stereochemically Pure 2‘-O-(2-Methoxyethyl)-Phosphorothioate Oligonucleotides
M. Li, H. L. Lightfoot, F. Halloy, A. L. Malinowska, C. Berk, A. Behera, D. Schümperli and J. Hall
Chem Commun 2017 (external pagePubMed)
“First synthesis and cell data from stereo-pure MOE PS-oligonucleotides”Prof. Jonathan Hall
“First synthesis and cell data from stereo-pure MOE PS-oligonucleotides”Prof. Jonathan Hall
“Could stereopurity reinvigorate the antisense field? ”C. and E. News 2016, 94, (26), 20-21
Critical 23S rRNA interactions for macrolide-dependent ribosome stalling on the ErmCL nascent peptide chain
M. Koch, J. Willi, U. Pradère, J. Hall and N. Polacek
Nucleic Acids Res. 2017 (external pagePubMed)