2021

Efficient Synthesis of 2'-O-Methoxyethyl Oligonucleotide-Cationic Peptide Conjugates

Dr. François Halloy, Dr. Alyssa C. Hill, Prof. Dr. Jonathan Hall

ChemMedChem. 2021 (external pagePubMed)

Single Nucleotide Resolution RNA–Protein Cross-Linking Mass Spectrometry: A Simple Extension of the CLIR-MS Workflow

RNA Synthesis Platform by ETH Zurich and NCCR RNA & Disease

Michael Götze, Chris P. Sarnowski, Tebbe de Vries, Anna Knörlein, Frédéric H.-T. Allain, Jonathan Hall, Ruedi Aebersold, and Alexander Leitner

Anal. Chem. 2021 (external pagePubMed)

Inosine Substitutions in RNA Activate Latent G-Quadruplexes

Timo Hagen, Artur Laski, Anneke Brümmer, Adam Pruška, Verena Schlösser, Antoine Cléry, Frédéric H-T Allain, Renato Zenobi, Sven Bergmann, Jonathan Hall

Journal of the American Chemical Society 2021 (external pagePubMed)

“^{The study reported in this manuscript is a novel idea, the sort of concept that elicits a why-didn't-I-think-of-that? response.}”
Reviewer 1

Design and Application of Mini-libraries of miRNA Probes for an Efficient and Versatile miRNA-mRNA Cross-linking

Anna L Malinowska, Artur Laski, Jonathan Hall*

Chemistry 2021 (external pagePubMed)

“^{Towards miR-CLIP for the masses}”
Prof. Jonathan Hall

Repurposing of glycine transport inhibitors for the treatment of erythropoietic protoporphyria

François Halloy, Pavithra S Iyer, Alice Ghidini, Veronika Lysenko, Jasmin Barman-Aksözen, Chia-Pei Grubenmann, Jessica Jucker, Nicole Wildner-Verhey van Wijk, Marc-David Ruepp, Elisabeth I Minder, Anna-Elisabeth Minder, Xiaoye Schneider-Yin, Alexandre PA Theocharides, Daniel Schümperli, Jonathan Hall*

Cell Chemical Biology 2021 (external pagePubMed)

“^{EPP - a new small molecule approach}”
Prof. Jonathan Hall

RNA-PROTACs: Degraders of RNA-Binding Proteins

Alice Ghidini, Antoine Cléry, François Halloy, Frédéric HT Allain, Jonathan Hall*

Angewandte Chemie International Edition 2021 (external pagePubMed)

“^{RNA-binding proteins as drug targets? Easy.} ”
Prof. Jonathan Hall

In vivo cytidine base editing of hepatocytes without detectable off-target mutations in RNA and DNA

Lukas Villiger, Tanja Rothgangl, Dominik Witzigmann, Rurika Oka, Paulo JC Lin, Weihong Qi, Sharan Janjuha, Christian Berk, Femke Ringnalda, Mitchell B Beattie, Markus Stoffel, Beat Thöny, Jonathan Hall, Hubert Rehrauer, Ruben van Boxtel, Ying K Tam, Gerald Schwank*

Nature Biomedical Engineering 2021 (external pagePubMed)

MiR-CLIP reveals iso-miR selective regulation in the miR-124 targetome

Yuluan Wang, Charlotte Soneson, Anna L Malinowska, Artur Laski, Souvik Ghosh, Alexander Kanitz, Luca FR Gebert, Mark D Robinson, Jonathan Hall

Nucleic Acids Research 2021 (external pagePubMed)

“^{The low hanging fruit is all gone... but we are not yet finished with miRNA biology!}”
Prof. Jonathan Hall